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Equation 7 · Einstein's Random Walk and the Mathematics of Genetic Drift

What does this equation mean?

D=RTN⋅16πkP,D = \frac{RT}{N}\cdot\frac{1}{6\pi k P},

Read the formula alongside the article passage below. Each part has a deeper page with its role in the equation, the supporting passage and nearby citations.

Start withRT
Divide byN
This relates toD
How to read the two sides of this formula. Follow the article passage for the meaning of each quantity.

This equation states an equality: the expressions on both sides have the same value under the article’s assumptions. Read the equation part by part below; each part has a contextual explanation and a link to its mathematical background.

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DD

Symbol D

D is part of the quantity the equation computes from the expression on the right.

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RR

Symbol R

the gas constant.

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TT

Symbol T

the absolute temperature.

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NN

Symbol N

N occurs below the fraction bar. The quantity above the bar is divided by this expression; zero is excluded as a denominator.

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π\pi

Symbol pi

pi occurs below the fraction bar. The quantity above the bar is divided by this expression; zero is excluded as a denominator.

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kk

Symbol k

k occurs below the fraction bar. The quantity above the bar is divided by this expression; zero is excluded as a denominator.

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PP

Symbol P

the radius.

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=

=

The expressions on both sides represent the same quantity under the stated assumptions.

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fraction

fraction

Divide the expression above the line by the one below it.

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multiplication

multiplication

Multiply the quantities on either side.

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RTRT

Numerator: RT

The complete quantity above the fraction bar.

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11

Numerator: 1

The complete quantity above the fraction bar.

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6πkP6\pi k P

Denominator: 6pi k P

The complete quantity below the fraction bar; it must be nonzero for this division.

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How to interpret it

With a fixed numerator, increasing a nonzero denominator reduces the fraction. Read it with the definitions, units, and assumptions supplied by the article.

What the article says around this equation

with the diffusion constant D fixed by measurable quantities. Einstein derived it explicitly, from the balance between the drag on a sphere of radius P in a fluid of viscosity k and the osmotic pressure driving diffusion, as D=RTN⋅16πkPD = \frac{RT}{N}\cdot\frac{1}{6\pi k P}. where R is the gas constant, T the absolute temperature, and N Avogadro’s number [ 1 ] . That last dependency was the trap door: if D could be read off a microscope by timing how far a particle wandered, and every other term in the equation was already known independently, then watching one particle jiggle became a way to count atoms.

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Sources cited in the surrounding passage

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