← Mathematical compendium

Published equation contexts

f^=∑i(P2(i)−P1(i)) (P4(i)−P1(i))∑i(P3(i)−P1(i)) (P4(i)−P1(i))\hat{f} = \frac{\sum_{i} (P_2(i) - P_1(i))\,(P_4(i) - P_1(i))}{\sum_{i} (P_3(i) - P_1(i))\,(P_4(i) - P_1(i))}

Why this formula appears here

The basic tool for estimating what fraction of a genome derives from an archaic population is comparative allele sharing: for a given modern population, count how much more genetic variation it shares with an archaic genome than a population known to lack that admixture does, and scale by how much variation the archaic and comparison genomes share with each other overall. A simplified version of the widely used D -statistic framework expresses this as: f^=∑i(P2(i)−P1(i)) (P4(i)−P1(i))∑i(P3(i)−P1(i)) (P4(i)−P1(i))\hat{f} = \frac{\sum_{i} (P_2(i) - P_1(i))\,(P_4(i) - P_1(i))}{\sum_{i} (P_3(i) - P_1(i))\,(P_4(i) - P_1(i))}. where P1P_1 through P4P_4 are allele frequencies at site i in an outgroup, a candidate-admixed population, a comparison population without the admixture, and the archaic source, respectively. The estimator exploits a simple…

Read the full article-specific guide →

Read the representative guide

ii

Symbol i

i appears in the bound of this sum. The bound states where the repeated operation starts, ends, or which values it includes.

Read this term in its guide →
P3P_3

Symbol P_3

P3P_3 occurs below the fraction bar. The quantity above the bar is divided by this expression; zero is excluded as a denominator.

Read this term in its guide →
∑i(P2(i)−P1(i)) (P4(i)−P1(i))\sum_{i} (P_2(i) - P_1(i))\,(P_4(i) - P_1(i))

Numerator: sum_i (P_2(i) - P_1(i))(P_4(i) - P_1(i))

The complete quantity above the fraction bar.

Read this term in its guide →
∑i(P3(i)−P1(i)) (P4(i)−P1(i))\sum_{i} (P_3(i) - P_1(i))\,(P_4(i) - P_1(i))

Denominator: sum_i (P_3(i) - P_1(i))(P_4(i) - P_1(i))

The complete quantity below the fraction bar; it must be nonzero for this division.

Read this term in its guide →
ii

Starting index or lower bound: i

This label says where the repeated addition, multiplication, or accumulation starts. Read its value or condition together with the article’s description of the index.

Read this term in its guide →
ii

Starting index or lower bound: i

This label says where the repeated addition, multiplication, or accumulation starts. Read its value or condition together with the article’s description of the index.

Read this term in its guide →

How to interpret it

With a fixed numerator, increasing a nonzero denominator reduces the fraction. Read it with the definitions, units, and assumptions supplied by the article.

Research cited beside this formula

Published contexts (1)

A symbol can carry a different meaning in another article. Each occurrence keeps its own guide and term definitions.

f^=∑i(P2(i)−P1(i)) (P4(i)−P1(i))∑i(P3(i)−P1(i)) (P4(i)−P1(i))\hat{f} = \frac{\sum_{i} (P_2(i) - P_1(i))\,(P_4(i) - P_1(i))}{\sum_{i} (P_3(i) - P_1(i))\,(P_4(i) - P_1(i))}

Equation 2 · Human Evolution

Hominin Evolution and Deep Prehistory: A First-Principles Introduction

This equation states an equality: the expressions on both sides have the same value under the article’s assumptions.

The basic tool for estimating what fraction of a genome derives from an archaic population is comparative allele sharing: for a given modern population, count how much more genetic variation it shares with an archaic genome than a population known to lack that admixture does, and scale by how much variation the archaic and comparison genomes share with each other overall. A simplified version of the widely used D -statistic framework expresses this as: f^=∑i(P2(i)−P1(i)) (P4(i)−P1(i))∑i(P3(i)−P1(i)) (P4(i)−P1(i))\hat{f} = \frac{\sum_{i} (P_2(i) - P_1(i))\,(P_4(i) - P_1(i))}{\sum_{i} (P_3(i) - P_1(i))\,(P_4(i) - P_1(i))}. where P1P_1 through P4P_4 are allele frequencies at site i in an outgroup, a candidate-admixed population, a comparison population without the admixture, and the archaic source, respectively. The estimator exploits a simple…

Equation guide → · Article →