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p=0.5p=0.5

Why this formula appears here

The same second-derivative operator acts on a diffusion term in both; only the variable and the coefficient it multiplies have changed. One honest difference is worth stating rather than smoothing over: Einstein’s D is a constant, fixed once by temperature and viscosity, while Kimura’s V(p) depends on the frequency itself, so the spread is fastest near p=0.5 and vanishes at the boundaries — an allele already fixed or already lost has nothing left to drift into [ 7 ] . The operator is identical; the coefficient it acts on has learned something about the biology.

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p=0.5p=0.5

Equation 24 · Einstein & Evolution

Einstein's Random Walk and the Mathematics of Genetic Drift

This equation states an equality: the expressions on both sides have the same value under the article’s assumptions.

The same second-derivative operator acts on a diffusion term in both; only the variable and the coefficient it multiplies have changed. One honest difference is worth stating rather than smoothing over: Einstein’s D is a constant, fixed once by temperature and viscosity, while Kimura’s V(p) depends on the frequency itself, so the spread is fastest near p=0.5 and vanishes at the boundaries — an allele already fixed or already lost has nothing left to drift into [ 7 ] . The operator is identical; the coefficient it acts on has learned something about the biology.

Meanings in this article

  • pp: the starting from frequency.
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