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Equation 21 · Part 1 · Evolutionary Biology and Ecology in Practice: An Advanced Technical Guide

Symbol hatN_e

N^e≈13 (r^2−1S)\hat{N}_e \approx \frac{1}{3\,(\hat{r}^2 - \tfrac{1}{S})}
N^e\hat{N}_e

What this part means

the not just the final.

Its job in the formula

hatNeN_e is a part of this expression. Its role is fixed by the surrounding article and by the operations shown in the formula.

Where the article explains it

The practical consequence practitioners have to internalize: r^2\hat{r}^2 is estimated with noise from a finite sample, and that noise itself creates apparent linkage disequilibrium indistinguishable from drift-generated LD unless it is explicitly subtracted — which is exactly what the 1/S term does, and why the estimator is only trustworthy when the sample size and locus count used to compute it are reported alongside the point estimate, not just the final N^e\hat{N}_e .

The passage around this formula

…subtracted — which is exactly what the 1/S term does, and why the estimator is only trustworthy when the sample size and locus count used to compute it are reported alongside the point estimate, not just the final N^e\hat{N}_e .

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Sources cited in the article section

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