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Equation 7 · What a Neural Recording Actually Records

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nn

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nn

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The empirical question of what n should be was addressed directly by Logothetis, Pauls, Augath, Trinath and Oeltermann, who recorded neural signals and BOLD simultaneously in monkey visual cortex. They found that local field potentials gave a better estimate of the BOLD response than multi-unit spiking did, and that at recording sites with transient responses the field potential was the only signal that significantly correlated with the haemodynamic response; they concluded that the signal reflects the input and intracortical processing of an area rather than its spiking output [ 10 ] . Logothetis later set out the general position at length, arguing that the ultimate limitations of the…
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The empirical question of what n should be was addressed directly by Logothetis, Pauls, Augath, Trinath and Oeltermann, who recorded neural signals and BOLD simultaneously in monkey visual cortex. They found that local field potentials gave a better estimate of the BOLD response than multi-unit spiking did, and that at recording sites with transient responses the field potential was the only signal that significantly correlated with the haemodynamic response; they concluded that the signal reflects the input and intracortical processing of an area rather than its spiking output [ 10 ] . Logothetis later set out the general position at length, arguing that the ultimate limitations of the method follow from the fact that it reflects mass action rather than from hardware, and that conclusions drawn from imaging data often ignore the actual limitations of the methodology [ 11 ] .

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