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Equation 6 · Part 1 · Structure from Sequence: What Protein Folding Prediction Did and Did Not Settle

Symbol nu

ν\nu
ν\nu

What this part means

nu is a part of this expression. Its role is fixed by the surrounding article and by the operations shown in the formula.

Its job in the formula

nu is a part of this expression. Its role is fixed by the surrounding article and by the operations shown in the formula.

The passage around this formula

Two things about this argument are routinely misreported. First, the specific numbers are illustrative and depend entirely on the assumed ν\nu and sampling rate — they are a scaling argument dressed as a calculation. What survives any choice of parameters is that the configuration count grows exponentially in L while folding times do not. Second, Levinthal was not proposing that folding is a random search and then expressing surprise. The arithmetic was constructed precisely to rule that mechanism out. The paradox is a paradox only for someone who assumed search in the first place.

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A variable is a named place for a value. Its letter is a local label: x can mean position in one formula and a data point in another.

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Sources cited in the article section

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