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Equation 1 · How Stochastic Thermodynamics and Complex Systems Actually Work

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ΔF\Delta F

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ΔF\Delta F

Symbol Δ F

Δ F is a part of this expression. Its role is fixed by the surrounding article and by the operations shown in the formula.

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change

change

Capital delta attached to a quantity marks a difference between two values of that quantity; the article’s sign convention determines the order.

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What the article says around this equation

Pull a molecule apart with an optical trap or an atomic force microscope and record the work done. Repeat the pull hundreds of times under identical conditions and the recorded work values scatter — sometimes wildly — because thermal noise contributes to every individual trajectory. That scatter looks like it should make the equilibrium free-energy difference Δ\Delta F unrecoverable from irreversible, far-from-equilibrium pulls.

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